The synthesis of novel spirocyclic N-aryl-substituted 2-thiopyrimidine-4,6-diones

A convenient and efficient method for the synthesis of new unsaturated spiro-annulated N-aryl-4,6-dioxopyrimidine-2-thione derivatives has been developed. The resulting compounds can be potential biological active molecules or precursors for further chemical modification. Aim. To develop the method...

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Bibliographic Details
Main Authors: N. I. Kobyzhcha, V. M. Holovatiuk, V. V. Rozhkov, V. I. Kashkovsky
Format: Article
Language:English
Published: National University of Pharmacy (Kharkiv, Ukraine) 2019-02-01
Series:Журнал органічної та фармацевтичної хімії
Subjects:
Online Access:http://ophcj.nuph.edu.ua/article/view/ophcj.19.962/159129