EGR3-HDAC6-IL-27 Axis Mediates Allergic Inflammation and Is Necessary for Tumorigenic Potential of Cancer Cells Enhanced by Allergic Inflammation-Promoted Cellular Interactions

EGR3-HDAC6-IL-27 Axis Mediates Allergic Inflammation and Is Necessary for Tumorigenic Potential of Cancer Cells Enhanced by Allergic Inflammation-Promoted Cellular Interactions

The objective of this study was to investigate mechanisms of allergic inflammation both in vitro and in vivo in details. For this, RNA sequencing was performed. Early growth response 3 gene (Egr3) was one of the most highly upregulated genes in rat basophilic leukemia (RBL2H3) cells stimulated by an...

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Bibliographic Details
Main Authors: Yoojung Kwon, Misun Kim, Youngmi Kim, Myeong Seon Jeong, Hyun Suk Jung, Dooil Jeoung
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
allergic inflammation
cellular interactions
EGR3
HDAC6
IL-27
MiR-182-5p
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.680441/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.680441/full

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