Common variants of the beta and gamma subunits of the epithelial sodium channel and their relation to plasma renin and aldosterone levels in essential hypertension

Common variants of the beta and gamma subunits of the epithelial sodium channel and their relation to plasma renin and aldosterone levels in essential hypertension

<p>Abstract</p> <p>Background</p> <p>Rare mutations of the epithelial sodium channel (ENaC) result in the monogenic hypertension form of Liddle's syndrome. We decided to screen for common variants in the ENaC βand γ subunits in patients with essential hypertension...

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Main Authors: Krusius Tom, Virtamo Jarmo, Miettinen Helena E, Piippo Kirsi, Fodstad Heidi, Helin Karri, Fyhrquist Frej, Tikkanen Tuula, Tikkanen Ilkka, Kontula Kimmo, Hannila-Handelberg Tuula, Sarna Seppo, Gautschi Ivan, Schild Laurent, Hiltunen Timo P
Format: Article
Language:English
Published: BMC 2005-01-01
Series:BMC Medical Genetics
Online Access:http://www.biomedcentral.com/1471-2350/6/4

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