Common variants of the beta and gamma subunits of the epithelial sodium channel and their relation to plasma renin and aldosterone levels in essential hypertension

<p>Abstract</p> <p>Background</p> <p>Rare mutations of the epithelial sodium channel (ENaC) result in the monogenic hypertension form of Liddle's syndrome. We decided to screen for common variants in the ENaC βand γ subunits in patients with essential hypertension...

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Main Authors: Krusius Tom, Virtamo Jarmo, Miettinen Helena E, Piippo Kirsi, Fodstad Heidi, Helin Karri, Fyhrquist Frej, Tikkanen Tuula, Tikkanen Ilkka, Kontula Kimmo, Hannila-Handelberg Tuula, Sarna Seppo, Gautschi Ivan, Schild Laurent, Hiltunen Timo P
Format: Article
Language:English
Published: BMC 2005-01-01
Series:BMC Medical Genetics
Online Access:http://www.biomedcentral.com/1471-2350/6/4