Prognostic and predictive biomarkers for hypoxic regions on breast cancer: advances and challenges Biomarcadores preditivos e prognósticos em regiões hipóxicas do câncer de mama: avanços e desafios

Hypoxia has been extensively studied in solid tumors mainly in breast cancers and it is commonly associated with chemotherapy and radiotherapy resistance. Hypoxia inducible factor (HIF)-1α is responsible for hypoxia in the tumor microenvironment and its molecular mechanisms as well as its t...

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Bibliographic Details
Main Authors: Moacyr Jesus Barreto de Melo Rêgo, Eduardo Isidoro Carneiro Beltrão
Format: Article
Language:English
Published: Sociedade Brasileira de Patologia Clínica 2013-02-01
Series:Jornal Brasileiro de Patologia e Medicina Laboratorial
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442013000100010