Prognostic and predictive biomarkers for hypoxic regions on breast cancer: advances and challenges Biomarcadores preditivos e prognósticos em regiões hipóxicas do câncer de mama: avanços e desafios
Hypoxia has been extensively studied in solid tumors mainly in breast cancers and it is commonly associated with chemotherapy and radiotherapy resistance. Hypoxia inducible factor (HIF)-1α is responsible for hypoxia in the tumor microenvironment and its molecular mechanisms as well as its t...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Sociedade Brasileira de Patologia Clínica
2013-02-01
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Series: | Jornal Brasileiro de Patologia e Medicina Laboratorial |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442013000100010 |