Organ-specific effects on inflammation and apoptosis of recombinant human activated protein C in a murine model of sepsis

There is legitimate interest in the effects of recombinant human activated protein C (rhAPC) on various organs and individual patients, but the specific effects on organ tissues during early sepsis remain unknown. Differences in the levels of organ damage may influence responses to drug therapy. We...

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Bibliographic Details
Main Authors: Tim-Philipp Simon, Hendrik Mueckenheim, Tobias Wagner, Christoph Sponholz, Ralf Alexander Claus, Joerg Saenger, Gernot Marx, Tobias Schuerholz
Format: Article
Language:English
Published: SAGE Publishing 2017-08-01
Series:European Journal of Inflammation
Online Access:https://doi.org/10.1177/1721727X17721088