Synergistic effects of hypofibrinolysis and genetic and acquired risk factors on the risk of a first venous thrombosis.

BACKGROUND: Previously, we demonstrated that hypofibrinolysis, a decreased capacity to dissolve a blood clot as measured with an overall clot lysis assay, increases the risk of venous thrombosis. Here, we investigated the combined effect of hypofibrinolysis with established risk factors associated w...

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Bibliographic Details
Main Authors: Mirjam E Meltzer, Ton Lisman, Carine J M Doggen, Philip G de Groot, Frits R Rosendaal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-05-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC2365975?pdf=render