Combination training in aging individuals modifies functional connectivity and cognition, and is potentially affected by dopamine-related genes.

<h4>Background</h4>Aging is a major co-risk factor in many neurodegenerative diseases. Cognitive enrichment positively affects the structural plasticity of the aging brain. In this study, we evaluated effects of a set of structured multimodal activities (Combination Training; CT) on cogn...

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Main Authors: Valentina Pieramico, Roberto Esposito, Francesca Sensi, Franco Cilli, Dante Mantini, Peter A Mattei, Valerio Frazzini, Domenico Ciavardelli, Valentina Gatta, Antonio Ferretti, Gian Luca Romani, Stefano L Sensi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22937122/pdf/?tool=EBI