Ex vivo characterization of Breg cells in patients with chronic Chagas disease

Abstract Despite the growing importance of the regulatory function of B cells in many infectious diseases, their immunosuppressive role remains elusive in chronic Chagas disease (CCD). Here, we studied the proportion of different B cell subsets and their capacity to secrete IL-10 ex vivo in peripher...

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Bibliographic Details
Main Authors: Magalí C. Girard, Gonzalo R. Acevedo, Micaela S. Ossowski, Marisa Fernández, Yolanda Hernández, Raúl Chadi, Karina A. Gómez
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-84765-x