THERAPEUTIC EFFECTS OF THE TRANSPLANTATION OF VEGF OVEREXPRESSING BONE MARROW MESENCHYMAL STEM CELLS IN THE HIPPOCAMPUS OF MURINE MODEL OF ALZHEIMER’S DISEASE

THERAPEUTIC EFFECTS OF THE TRANSPLANTATION OF VEGF OVEREXPRESSING BONE MARROW MESENCHYMAL STEM CELLS IN THE HIPPOCAMPUS OF MURINE MODEL OF ALZHEIMER’S DISEASE

Alzheimer´s disease (AD) is clinically characterized by progressive memory loss, behavioural and learning dysfunction and cognitive deficits, such as alterations in social interactions. The major pathological features of AD are the formation of senile plaques and neurofibrillary tangles together with...

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Bibliographic Details
Main Authors: Karina de Oliveira Garcia, Felipe Leite Ornellas, Priscila eMatsumoto, Camilla de Lima Patti, Luiz E Mello, Roberto eFrussa-Filho, Sang Won Han, Beatriz Monteiro Longo
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-03-01
Series:Frontiers in Aging Neuroscience
Subjects:
Alzheimer's disease
VEGF
Angiogenesis
mesenchymal stem cell
memory deficits
amyloid clearance.
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00030/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00030/full

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