MMP-1 is a (pre-)invasive factor in Barrett-associated esophageal adenocarcinomas and is associated with positive lymph node status

<p>Abstract</p> <p>Background</p> <p>Esophageal adenocarcinomas (EACs) arise due to gastroesophageal reflux, with Barrett's esophagus (BE) regarded as precancerous lesion. Matrix metalloproteinases (MMPs) might play a role during the multistep carcinogenetic proces...

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Bibliographic Details
Main Authors: Otto Christoph, Gattenlöhner Stefan, Höfelmayr Andreas, Reiber Christoph, Stuermer Luisa, Kircher Stefan, Lazariotou Maria, Grimm Martin, Germer Christoph T, von Rahden Burkhard HA
Format: Article
Language:English
Published: BMC 2010-10-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/8/1/99