Methanolic extract of Abrus precatorius promotes breast cancer MDA-MB-231 cell death by inducing cell cycle arrest at G0/G1 and upregulating Bax

Methanolic extract of Abrus precatorius promotes breast cancer MDA-MB-231 cell death by inducing cell cycle arrest at G0/G1 and upregulating Bax

Objective: To determine the anti-proliferative activity of Abrus precatorius (A. precatorius) leaf extracts and their effect on cell death. Methods: A. precatorius leaves were extracted successively with hexane, ethyl acetate and methanol by Soxhlet extraction. Aqueous extract was prepared by decoct...

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Bibliographic Details
Main Authors: Wan Suriyani Wan-Ibrahim, Norzila Ismail, Siti Farhanah Mohd-Salleh, Aidy Irman Yajid, Michael Pak-Kai Wong, Mohd Nizam Md Hashim
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Asian Pacific Journal of Tropical Biomedicine
Subjects:
abrus precatorius
mda-mb-231
apoptosis
cell cycle
breast cancer
Online Access:http://www.apjtb.org/article.asp?issn=2221-1691;year=2019;volume=9;issue=6;spage=249;epage=256;aulast=Wan-Ibrahim

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http://www.apjtb.org/article.asp?issn=2221-1691;year=2019;volume=9;issue=6;spage=249;epage=256;aulast=Wan-Ibrahim

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