Comparison of methods for estimating the nucleotide substitution matrix

<p>Abstract</p> <p>Background</p> <p>The nucleotide substitution rate matrix is a key parameter of molecular evolution. Several methods for inferring this parameter have been proposed, with different mathematical bases. These methods include counting sequence difference...

Full description

Bibliographic Details
Main Authors: Huttley Gavin A, Yap Von Bing, McDonald Daniel, Oscamou Maribeth, Lladser Manuel E, Knight Rob
Format: Article
Language:English
Published: BMC 2008-12-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/9/511