Mitochondrial DNA Rearrangement Spectrum in Brain Tissue of Alzheimer's Disease: Analysis of 13 Cases.

Mitochondrial dysfunction may play a central role in the pathologic process of Alzheimer's disease (AD), but there is still a scarcity of data that directly links the pathology of AD with the alteration of mitochondrial DNA. This study aimed to provide a comprehensive assessment of mtDNA rearra...

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Bibliographic Details
Main Authors: Yucai Chen, Changsheng Liu, William Davis Parker, Hongyi Chen, Thomas G Beach, Xinhua Liu, Geidy E Serrano, Yanfen Lu, Jianjun Huang, Kunfang Yang, Chunmei Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4907522?pdf=render