LncHOXA10 drives liver TICs self-renewal and tumorigenesis via HOXA10 transcription activation

Abstract Background Liver cancer is one of the most deadly cancers in the world. There are various cells in liver tumor bulk, including liver tumor initiating cells (TICs), which account for liver tumorigenesis, drug resistance, relapse and metastasis. The homeobox (HOX) transcription factors play c...

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Bibliographic Details
Main Authors: Ming Shao, Qiankun Yang, Weitao Zhu, Huifang Jin, Jing Wang, Jie Song, Yongkui Kong, Xianping Lv
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Molecular Cancer
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12943-018-0921-y