Clinical Usefulness of HLA-B∗58:01 Genotyping in Gouty Arthritis
Allopurinol is an effective urate lowering agent but may lead to rare but life-threatening severe cutaneous adverse reactions (SCAR). Genetic predisposition, age, sex, renal function, dosage and concomitant diuretic use are known risk factors of allopurinol related SCAR. Among these factors, HLA-B∗5...
Main Authors: | Carrel Ka Lung Yu, Chi Chiu Mok |
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Format: | Article |
Language: | English |
Published: |
World Scientific Publishing
2019-07-01
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Series: | Journal of Clinical Rheumatology and Immunology |
Subjects: | |
Online Access: | http://www.worldscientific.com/doi/epdf/10.1142/S2661341719300027 |
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