Clinical Usefulness of HLA-B∗58:01 Genotyping in Gouty Arthritis
Allopurinol is an effective urate lowering agent but may lead to rare but life-threatening severe cutaneous adverse reactions (SCAR). Genetic predisposition, age, sex, renal function, dosage and concomitant diuretic use are known risk factors of allopurinol related SCAR. Among these factors, HLA-B∗5...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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World Scientific Publishing
2019-07-01
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| Series: | Journal of Clinical Rheumatology and Immunology |
| Subjects: | |
| Online Access: | http://www.worldscientific.com/doi/epdf/10.1142/S2661341719300027 |