Di’ao Xinxuekang Capsule, a Chinese Medicinal Product, Decreases Serum Lipids Levels in High-Fat Diet-Fed ApoE–/– Mice by Downregulating PCSK9

Di’ao Xinxuekang Capsule, a Chinese Medicinal Product, Decreases Serum Lipids Levels in High-Fat Diet-Fed ApoE–/– Mice by Downregulating PCSK9

Numerous risk factors are responsible for the development of atherosclerosis, for which an increased serum level of low-density lipoprotein cholesterol (LDL-C) is a driving force. By binding to the low-density lipoprotein cholesterol receptor (LDLR) and inducing LDLR degradation, proprotein converta...

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Bibliographic Details
Main Authors: Liping Qu, Didi Li, Xiaoping Gao, Yongwei Li, Jianming Wu, Wenjun Zou
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Pharmacology
Subjects:
Di’ao Xinxuekang
LDL-C
PCSK9
LDLR
ApoE–/– mice
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01170/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.01170/full

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