Roles of PI3K/AKT/GSK3/mTOR Pathway in Cell Signaling of Mental Illnesses

Several pharmacological agents acting on monoamine neurotransmission are used for the management of mental illnesses. Regulation of PI3K/AKT and GSK3 pathways may constitute an important signaling center in the subcellular integration of the synaptic neurotransmission. The pathways also modulate neu...

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Bibliographic Details
Main Authors: Yasuko Kitagishi, Mayumi Kobayashi, Kanae Kikuta, Satoru Matsuda
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Depression Research and Treatment
Online Access:http://dx.doi.org/10.1155/2012/752563