First-passage time analysis of a one-dimensional diffusion-reaction model: application to protein transport along DNA

<p>Abstract</p> <p>Background</p> <p>Proteins search along the DNA for targets, such as transcription initiation sequences, according to one-dimensional diffusion, which is interrupted by micro- and macro-hopping events and intersegmental transfers that occur under clos...

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Bibliographic Details
Main Authors: Perkins Edward J, Mayo Michael L, Ghosh Preetam
Format: Article
Language:English
Published: BMC 2011-10-01
Series:BMC Bioinformatics