Cell-free 3D scaffold with two-stage delivery of miRNA-26a to regenerate critical-sized bone defects
A challenge in regenerative medicine is the development of cell-free, non-immunogenic miRNA-delivering scaffolds. Here the authors design a cell-free scaffold capable of efficient and prolonged delivery of miRNA-26a to endogenous cells and show that it can regenerate a full-thickness calvarial bone...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2016-01-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms10376 |