Wingless-Type MMTV Integration Site Family Member 5a Is a Key Secreted Islet Stellate Cell-Derived Product that Regulates Islet Function

Background. Emerging evidence suggests that T2DM is attributable to the dysfunction of β-cells and the activation of islet stellate cells (ISCs). The wingless-type MMTV integration site family member 5a (Wnt5a)/frizzled 5 (Fzd5) signalling pathway might take part in this process. Our study is aimed...

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Bibliographic Details
Main Authors: Wei Xu, Jun Liang, H. F. Geng, Jun Lu, Rui Li, X. L. Wang, Qian Lv, Ying Liu, Jie Wang, X. K. Liu, Peter M. Jones, Zl Sun
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2019/7870109