Chronic intermittent hypoxia disrupts cardiorespiratory homeostasis and gut microbiota composition in adult male guinea-pigsResearch in context

Background: Carotid body (peripheral oxygen sensor) sensitisation is pivotal in the development of chronic intermittent hypoxia (CIH)-induced hypertension. We sought to determine if exposure to CIH, modelling human sleep apnoea, adversely affects cardiorespiratory control in guinea-pigs, a species w...

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Bibliographic Details
Main Authors: Eric F. Lucking, Karen M. O'Connor, Conall R. Strain, Fiona Fouhy, Thomaz F.S. Bastiaanssen, David P. Burns, Anna V. Golubeva, Catherine Stanton, Gerard Clarke, John F. Cryan, Ken D. O'Halloran
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396418305036