Advances in flux balance analysis by integrating machine learning and mechanism-based models

The availability of multi-omics data sets and genome-scale metabolic models for various organisms provide a platform for modeling and analyzing genotype-to-phenotype relationships. Flux balance analysis is the main tool for predicting flux distributions in genome-scale metabolic models and various d...

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Bibliographic Details
Main Authors: Ankur Sahu, Mary-Ann Blätke, Jędrzej Jakub Szymański, Nadine Töpfer
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037021003354