Effects of dietary phosphate on adynamic bone disease in rats with chronic kidney disease--role of sclerostin?

High phosphate intake is known to aggravate renal osteodystrophy along various pathogenetic pathways. Recent studies have raised the possibility that dysregulation of the osteocyte Wnt/β-catenin signaling pathway is also involved in chronic kidney disease (CKD)-related bone disease. We investigated...

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Main Authors: Juliana C Ferreira, Guaraciaba O Ferrari, Katia R Neves, Raquel T Cavallari, Wagner V Dominguez, Luciene M Dos Reis, Fabiana G Graciolli, Elizabeth C Oliveira, Shiguang Liu, Yves Sabbagh, Vanda Jorgetti, Susan Schiavi, Rosa M A Moysés
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24236156/?tool=EBI