Single-Dose Toxicity Study on ML171, a Selective NOX1 Inhibitor, in Mice

Background. ML171 is a potent nicotinamide adenine dinucleotide phosphate oxidase (NOX) inhibitor with isoform selectivity only for NOX1. This study is aimed at investigating the safety of ML171 after a single intraperitoneal (IP) injection in mice. Methods. The toxicity of a single dose of ML171 wa...

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Bibliographic Details
Main Authors: Se-Hyun Oh, Ji-Sun Ahn, Eun-Joo Oh, You-Jin Kim, Ju-Min Yook, Jeong-Hoon Lim, Hee-Yeon Jung, Ji-Young Choi, Chan-Duck Kim, Sun-Hee Park, Yong-Lim Kim, Jang-Hee Cho
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2021/5515478