The last common ancestor of animals lacked the HIF pathway and respired in low-oxygen environments

The last common ancestor of animals lacked the HIF pathway and respired in low-oxygen environments

Animals have a carefully orchestrated relationship with oxygen. When exposed to low environmental oxygen concentrations, and during periods of increased energy expenditure, animals maintain cellular oxygen homeostasis by enhancing internal oxygen delivery, and by enabling the anaerobic production of...

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Bibliographic Details
Main Authors: Daniel B Mills, Warren R Francis, Sergio Vargas, Morten Larsen, Coen PH Elemans, Donald E Canfield, Gert Wörheide
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-02-01
Series:eLife
Subjects:
hypoxia-inducible factor
Tethya wilhelma
oxygen sensing
early animal evolution
Porifera
Online Access:https://elifesciences.org/articles/31176

Internet

https://elifesciences.org/articles/31176

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