The c-Met receptor tyrosine kinase inhibitor MP470 radiosensitizes glioblastoma cells
<p>Abstract</p> <p>Purpose</p> <p>Glioblastoma multiforme (GBM) is resistant to current cytotoxic therapies, in part because of enhanced DNA repair. Activation of the receptor tyrosine kinase c-Met has been shown to protect cancer cells from DNA damage. We hypothesized...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2009-12-01
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Series: | Radiation Oncology |
Online Access: | http://www.ro-journal.com/content/4/1/69 |