Pharmacometrics as an instrument of clinical pharmacology for optimization of drugs dosing regimens during pregnancy
Changes in maternal physiology and metabolic during pregnancy influence pharmacokinetics and illustrate that standard adult dosing is likely to be incorrect during pregnancy. Different pharmacometric approaches are available for design and analysis of clinical studies during pregnancy. Physiological...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Saratov State Medical University
2014-03-01
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| Series: | Саратовский научно-медицинский журнал |
| Subjects: | |
| Online Access: | http://www.ssmj.ru/system/files/2014_01-01_199-203.pdf |