Diversity-Oriented Synthesis and Chemoinformatic Analysis of the Molecular Diversity of sp3-Rich Morpholine Peptidomimetics

Diversity-Oriented Synthesis and Chemoinformatic Analysis of the Molecular Diversity of sp3-Rich Morpholine Peptidomimetics

Diversity-Oriented Synthesis (DOS) consists of generating structurally diverse compounds from a complexity-generating reaction followed by cyclization steps and appendage diversity. DOS has gathered interest to systematically explore the chemical space by generating high-quality small-molecule colle...

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Bibliographic Details
Main Authors: Elena Lenci, Riccardo Innocenti, Gloria Menchi, Andrea Trabocchi
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Chemistry
Subjects:
chemical diversity
heterocycles
amino acids
carbohydrates
small molecules
building blocks
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2018.00522/full

Internet

https://www.frontiersin.org/article/10.3389/fchem.2018.00522/full

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