A Framework for the Development of Integrated and Computationally Feasible Models of Large-Scale Mammalian Cell Bioreactors

Industrialization of bioreactors has been achieved by applying several core concepts of science and engineering. Modeling has deepened the understanding of biological and physical phenomena. In this paper, the state of existing cell culture models is summarized. A framework for development of dynami...

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Bibliographic Details
Main Authors: Parham Farzan, Marianthi G. Ierapetritou
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Processes
Subjects:
Online Access:http://www.mdpi.com/2227-9717/6/7/82