Highly active antiretroviral therapies are effective against HIV-1 cell-to-cell transmission.

HIV-1 cell-to-cell transmission allows for 2-3 orders of magnitude more efficient viral spread than cell-free dissemination. The high local multiplicity of infection (MOI) observed at cell-cell contact sites may lower the efficacy of antiretroviral therapies (ART). Here we test the efficacy of commo...

Full description

Bibliographic Details
Main Authors: Luis M Agosto, Peng Zhong, James Munro, Walther Mothes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-02-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24586176/pdf/?tool=EBI