Comparison of p53 and the PDZ domain containing protein MAGI-3 regulation by the E6 protein from high-risk human papillomaviruses

<p>Abstract</p> <p>Central to cellular transformation caused by human papillomaviruses (HPVs) is the ability of E6 proteins to target cellular p53 and proteins containing PDZ domains, including MAGI-3, for degradation. The aim of this study was to compare E6-mediated degradation of...

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Bibliographic Details
Main Authors: Coutlee Francois, Banks Lawrence, Thomas Miranda, Ainsworth Julia, Matlashewski Greg
Format: Article
Language:English
Published: BMC 2008-06-01
Series:Virology Journal
Online Access:http://www.virologyj.com/content/5/1/67