In-depth method assessments of differentially expressed protein detection for shotgun proteomics data with missing values
Abstract Considering as one of the major goals in quantitative proteomics, detection of the differentially expressed proteins (DEPs) plays an important role in biomarker selection and clinical diagnostics. There have been plenty of algorithms and tools focusing on DEP detection in proteomics researc...
Main Authors: | Jinxia Wang, Liwei Li, Tao Chen, Jie Ma, Yunping Zhu, Jujuan Zhuang, Cheng Chang |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-06-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-03650-8 |
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