In-depth method assessments of differentially expressed protein detection for shotgun proteomics data with missing values

Abstract Considering as one of the major goals in quantitative proteomics, detection of the differentially expressed proteins (DEPs) plays an important role in biomarker selection and clinical diagnostics. There have been plenty of algorithms and tools focusing on DEP detection in proteomics researc...

Full description

Bibliographic Details
Main Authors: Jinxia Wang, Liwei Li, Tao Chen, Jie Ma, Yunping Zhu, Jujuan Zhuang, Cheng Chang
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-03650-8