Insights into T cell recognition of antigen: Significance of two-dimensional kinetic parameters

The kinetic parameters governing T cell activation have been intensely studied for over a decade. However, the details of how the various aspects of receptor:ligand interactions culminate in T cell activation remains shrouded in mystery. Initial measurements were generated using surface plasmon res...

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Bibliographic Details
Main Authors: Lindsay J Edwards, Veronika I Zarnitsyna, Jennifer D Hood, Brian eEvavold, Cheng eZhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-04-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00086/full