Low‐dose caffeine administration increases fatty acid utilization and mitochondrial turnover in C2C12 skeletal myotubes

Abstract Caffeine has been shown to directly increase fatty acid oxidation, in part, by promoting mitochondrial biogenesis. Mitochondrial biogenesis is often coupled with mitophagy, the autophagy‐lysosomal degradation of mitochondria. Increased mitochondrial biogenesis and mitophagy promote mitochon...

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Bibliographic Details
Main Authors: David S. Enyart, Chelsea L. Crocker, Jennifer R. Stansell, Madeleine Cutrone, Meghann M. Dintino, Stephen T. Kinsey, Stephan L. Brown, Bradley L. Baumgarner
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.14340