An Approach to Maximize Retrograde Transport Based on the Spatial Distribution of Motor Endplates in Mouse Hindlimb Muscles

An Approach to Maximize Retrograde Transport Based on the Spatial Distribution of Motor Endplates in Mouse Hindlimb Muscles

Knowledge regarding the relationship between muscles and the corresponding motor neurons would allow therapeutic genes to transport into specific spinal cord segments. Retrograde tracing technique by targeting the motor endplate (MEP), a highly specialized structure that offers direct access to the...

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Bibliographic Details
Main Authors: Jianyi Xu, Ang Xuan, Zhang Liu, Yusha Li, Jingtan Zhu, Yingtao Yao, Tingting Yu, Dan Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Cellular Neuroscience
Subjects:
motor endplate
spatial distribution
3D intramuscular injection
retrograde transport
tissue optical clearing
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2021.707982/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2021.707982/full

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