Retinoic acid signaling and the evolution of chordates

Retinoic acid signaling and the evolution of chordates

<p>In chordates, which comprise urochordates, cephalochordates and vertebrates, the vitamin A-derived morphogen retinoic acid (RA) has a pivotal role during development. Altering levels of endogenous RA signaling during early embryology leads to severe malformations, mainly due to incorrect po...

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Bibliographic Details
Format: Article
Language:English
Published: Ivyspring International Publisher 2006-04-01
Series:International Journal of Biological Sciences
Subjects:
amphioxus
anteroposterior patterning
<italic>Branchiostoma</italic>
deuterostomes
<italic>Hox</italic>
invertebrate-to-vertebrate transition
phylogeny
Online Access:http://www.biolsci.org/v02p0038.htm

Internet

http://www.biolsci.org/v02p0038.htm

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