Down-regulation of METTL3-LYN m6A-IGF2BP2 pathway inhibits endothelial cell migration

Objective To investigate the effect of methyltransferase like 3 (METTL3) on the migration of human umbilical vein endothelial cells (HUVECs), and explore the underlying mechanism preliminarily. Methods The sgRNA targeting the first exon of METTL3 was designed with aid of online platform and synthes...

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Bibliographic Details
Main Authors: BAI Qin, CHEN Yanhua, LU Yao, WU Huang, WEN Aiqing
Format: Article
Language:zho
Published: Editorial Office of Journal of Third Military Medical University 2021-05-01
Series:Di-san junyi daxue xuebao
Subjects:
Online Access:http://aammt.tmmu.edu.cn/Upload/rhtml/202011144.htm