Excitatory GABA: How a correct observation may turn out to be an experimental artifact
The concept of an excitatory/inhibitory switch of GABA action during development is based on results mainly obtained in brain slices. However, in vivo measurements, as well as observations made in intact in vitro structures, indicate that GABA is inhibitory in rodents at very early neonatal stages....
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2012-04-01
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Series: | Frontiers in Pharmacology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fphar.2012.00065/full |