Excitatory GABA: How a correct observation may turn out to be an experimental artifact

The concept of an excitatory/inhibitory switch of GABA action during development is based on results mainly obtained in brain slices. However, in vivo measurements, as well as observations made in intact in vitro structures, indicate that GABA is inhibitory in rodents at very early neonatal stages....

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Bibliographic Details
Main Authors: Piotr eBregestovski, Christophe eBernard
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-04-01
Series:Frontiers in Pharmacology
Subjects:
GDP
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2012.00065/full