Plasmin degradation of the alpha chain of fibrinogen/fibrin: improved activation constant and activity determination in assays for tissue plasminogen activator = Degradación por la plasmina de la cadena alfa del fibrinógeno/fibrina: mejoría de la constante de activación y determinación de la actividad en ensayos para el activador del plasminógeno tisular

Objectives. The aim of this investigation was to increase the efficiency of ternary complex formation (fibrin-plasminogen-tissue-plasminogen activator) in the degradation process of the three-dimensional soluble fibrin monomer. Materials and methods. Fibrinogen was purified from human plasma by r...

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Bibliographic Details
Main Authors: Garcés Parada, Tatiana María, Quijano Parra, Alfonso, Arbeláez Ramírez, Luis Fernando
Format: Article
Language:Spanish
Published: Universidad de Antioquia 2013-07-01
Series:Iatreia
Subjects:
Online Access:http://www.iatreia.udea.edu.co/index.php/iatreia/article/view/13669/13596