Increased oxidative protein and DNA damage but decreased stress response in the aged brain following experimental stroke
Aged individuals experience the highest rate of stroke and have less functional recovery, but do not have larger infarcts. We hypothesized that aged individuals experience greater sublethal damage in peri-infarct cortex. Focal cortical stroke was produced in aged and young adult animals. After 30 mi...
Main Authors: | Songlin Li, Jian Zheng, S. Thomas Carmichael |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2005-04-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996104002931 |
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