Increased oxidative protein and DNA damage but decreased stress response in the aged brain following experimental stroke

Aged individuals experience the highest rate of stroke and have less functional recovery, but do not have larger infarcts. We hypothesized that aged individuals experience greater sublethal damage in peri-infarct cortex. Focal cortical stroke was produced in aged and young adult animals. After 30 mi...

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Bibliographic Details
Main Authors: Songlin Li, Jian Zheng, S. Thomas Carmichael
Format: Article
Language:English
Published: Elsevier 2005-04-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996104002931