Physical Characterization of Colorectal Cancer Spheroids and Evaluation of NK Cell Infiltration Through a Flow-Based Analysis

Physical Characterization of Colorectal Cancer Spheroids and Evaluation of NK Cell Infiltration Through a Flow-Based Analysis

To improve pathogenetic studies in cancer development and reliable preclinical testing of anti-cancer treatments, three-dimensional (3D) cultures, including spheroids, have been widely recognized as more physiologically relevant in vitro models of in vivo tumor behavior. Currently, the generation of...

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Bibliographic Details
Main Authors: Azzurra Sargenti, Francesco Musmeci, Francesco Bacchi, Cecilia Delprete, Domenico Andrea Cristaldi, Federica Cannas, Simone Bonetti, Simone Pasqua, Daniele Gazzola, Delfina Costa, Federico Villa, Maria Raffaella Zocchi, Alessandro Poggi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Immunology
Subjects:
colorectal cancer
spheroid
natural killer cells
mass density
microfluidics
weight
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.564887/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.564887/full

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