TAp63α Is Involved in Tobacco Smoke-Induced Lung Cancer EMT and the Anti-cancer Activity of Curcumin via miR-19 Transcriptional Suppression

TAp63α Is Involved in Tobacco Smoke-Induced Lung Cancer EMT and the Anti-cancer Activity of Curcumin via miR-19 Transcriptional Suppression

As a key risk factor for lung cancer, tobacco smoke (TS) influences several cellular processes, including epithelial-mesenchymal transition (EMT). TAp63α is a crucial transcription factor involved in tumor progression. The present study was designed to investigate the potential role and underlying m...

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Bibliographic Details
Main Authors: Chunfeng Xie, Jianyun Zhu, Xue Yang, Cong Huang, Liping Zhou, Zili Meng, Xiaoting Li, Caiyun Zhong
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
TAp63α
lung cancer
miR-19
EMT
curcumin
tobacco smoke
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.645402/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.645402/full

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