A CDK-regulated chromatin segregase promoting chromosome replication

How cells coordinate chromatin dynamics with the cell cycle machinery to promote genome duplication during S phase is still a matter of study. Here the authors reveal by in vitro reconstitution assays that the AAA + -ATPase containing Yta7 protein in S. cerevisiae promotes chromatin.

Bibliographic Details
Main Authors: Erika Chacin, Priyanka Bansal, Karl-Uwe Reusswig, Luis M. Diaz-Santin, Pedro Ortega, Petra Vizjak, Belen Gómez-González, Felix Müller-Planitz, Andrés Aguilera, Boris Pfander, Alan C. M. Cheung, Christoph F. Kurat
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-25424-7