A multifaceted analysis of HIV-1 protease multidrug resistance phenotypes

<p>Abstract</p> <p>Background</p> <p>Great strides have been made in the effective treatment of HIV-1 with the development of second-generation protease inhibitors (PIs) that are effective against historically multi-PI-resistant HIV-1 variants. Nevertheless, mutation pa...

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Bibliographic Details
Main Authors: Doherty Kathleen M, Nakka Priyanka, King Bracken M, Rhee Soo-Yon, Holmes Susan P, Shafer Robert W, Radhakrishnan Mala L
Format: Article
Language:English
Published: BMC 2011-12-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/12/477