Elevated mutation rate during meiosis in Saccharomyces cerevisiae.

Mutations accumulate during all stages of growth, but only germ line mutations contribute to evolution. While meiosis contributes to evolution by reassortment of parental alleles, we show here that the process itself is inherently mutagenic. We have previously shown that the DNA synthesis associated...

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Bibliographic Details
Main Authors: Alison Rattray, Gustavo Santoyo, Brenda Shafer, Jeffrey N Strathern
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4287439?pdf=render