Mechanism of Vascular Toxicity in Rats Subjected to Treatment with a Tyrosine Kinase Inhibitor

Mechanism of Vascular Toxicity in Rats Subjected to Treatment with a Tyrosine Kinase Inhibitor

Sunitinib (Su) is a tyrosine kinase inhibitor with antiangiogenic and antineoplastic effects that is recommended therapy for renal cell carcinoma, gastrointestinal stromal tumors, and pancreatic neuroendocrine tumors. Arterial hypertension is one of the adverse effects observed in the treatment with...

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Bibliographic Details
Main Authors: Claudia Reyes-Goya, Álvaro Santana-Garrido, Estefanía Soto-Astacio, Óscar Aramburu, Sonia Zambrano, Alfonso Mate, Carmen M. Vázquez
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Toxics
Subjects:
arterial hypertension
endothelial dysfunction
tyrosine kinase inhibitor
vascular remodeling
Online Access:https://www.mdpi.com/2305-6304/8/3/49

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https://www.mdpi.com/2305-6304/8/3/49

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